Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519638 | 0.92 | BCL2L1 (0.42) | P4HTMBCL2L1MCL1NPC1RAB9A | |
| SCHEMBL9516093 | 0.88 | HSD11B1 (0.43) | P4HTMBCL2L1MCL1SCN5ASCN9A | |
| SCHEMBL9517939 | 0.87 | EGFR (0.40) | P4HTMNPC1RAB9AEGFRSCN5A | |
| SCHEMBL9517265 | 0.84 | EGFR (0.41) | P4HTMEGFRSCN5ASCN9AL3MBTL1 | |
| SCHEMBL9516977 | 0.83 | EGFR (0.44) | P4HTMNPC1RAB9AEGFRMEN1 | |
| SCHEMBL9517170 | 0.82 | HDAC1 (0.39) | P4HTMBCL2L1MCL1HDAC6SLC6A9 | |
| SCHEMBL9515729 | 0.82 | BCL2L1 (0.40) | P4HTMBCL2L1MCL1NPC1RAB9A | |
| SCHEMBL9516994 | 0.79 | SCN9A (0.38) | P4HTMEGFRSCN5ASCN9ASMN1; SMN2 | |
| SCHEMBL9517911 | 0.78 | CXCR1 (0.37) | P4HTMMEN1KMT2AHDAC6CXCR2 | |
| SCHEMBL9566848 | 0.78 | P4HTM (0.55) | P4HTMNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |