Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967736 | 1.00 | NPSR1 (0.38) | NPSR1RXRARARBRARGSLC6A4 | |
| SCHEMBL8967697 | 0.89 | RXRA (0.44) | RXRARARBRARGSLC6A4SLC6A2 | |
| SCHEMBL9515730 | 0.83 | MEN1 (0.34) | RXRARARBRARGSLC6A4SLC6A2 | |
| SCHEMBL27399659 | 0.82 | NPSR1 (0.40) | NPSR1SLC6A4SLC6A2SLC6A3BACE1 | |
| SCHEMBL9455450 | 0.82 | MMP1 (0.38) | RXRARARBRARGSLC6A4SLC6A2 | |
| SCHEMBL27364424 | 0.82 | MMP1 (0.38) | RXRARARBRARGSLC6A4SLC6A2 | |
| SCHEMBL9515299 | 0.81 | HPGD (0.40) | RXRARARBRARGSLC6A4SLC6A2 | |
| SCHEMBL9455335 | 0.80 | MMP1 (0.36) | — | |
| SCHEMBL27359328 | 0.79 | F11 (0.32) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8967734 | 0.77 | MAOB (0.32) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326755-A | Contain cyclopropane ring | ROUSSEL UCLAF | 1994-07-05 | — | — | US | disclosed |