Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TPH1 | P17752 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28385334 | 0.85 | L3MBTL1 (0.44) | AKR1B1ARMEN1NPC1RAB9A | |
| SCHEMBL2558366 | 0.81 | AKR1B1 (0.55) | AKR1B1TDP1PTGS2BCAT2CXCL8 | |
| SCHEMBL8950915 | 0.80 | AKR1B1 (0.50) | AKR1B1TDP1PTGS2BCAT2MEN1 | |
| SCHEMBL462452 | 0.80 | AR (0.49) | ARMEN1NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL5510044 | 0.78 | AR (0.47) | ARMEN1NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL31500442 | 0.78 | AR (0.47) | ARMEN1NPC1RAB9AKMT2A | |
| SCHEMBL11112921 | 0.78 | AKR1B1 (0.52) | AKR1B1TDP1PTGS2BCAT2CXCL8 | |
| SCHEMBL5317695 | 0.76 | AR (0.46) | ARMEN1NPC1RAB9AKMT2A | |
| SCHEMBL7674635 | 0.76 | AR (0.46) | ARMEN1NPC1RAB9AKMT2A | |
| SCHEMBL1241839 | 0.76 | AR (0.53) | TDP1ARMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361408-B1 | Improved bone cement | WOLLF & KAABER AS (DK) | 1993-11-24 | — | — | EP | claimed |
| WO-1990003193-A1 | BONE CEMENT | WOLFF & KAABER A/S (DK) | 1990-04-05 | — | — | WO | claimed |
| EP-0361408-A2 | Improved bone cement | Wolff & Kaaber A/S (DK) | 1990-04-04 | — | — | EP | claimed |
| US-4910259-A | Acrylated polymer | WOLFF & KAABER A/S (DK) | 1990-03-20 | — | — | US | claimed |
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |
| US-4486179-A | ESTERS OF SYRINGIC ACID AS ANTICARIES AGENTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1984-12-04 | — | — | US | disclosed |