Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | HTR3A | P46098 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24548502 | 0.89 | LMNA (0.42) | LMNAHAO1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11163658 | 0.89 | TAAR1 (0.44) | LMNAHAO1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10856259 | 0.87 | LMNA (0.41) | LMNAHAO1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20171522 | 0.86 | LMNA (0.45) | LMNAHAO1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14564993 | 0.84 | LMNA (0.44) | LMNAHAO1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10859248 | 0.82 | LMNA (0.46) | LMNAHAO1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30753704 | 0.81 | L3MBTL1 (0.46) | LMNASMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL7691152 | 0.79 | LMNA (0.47) | LMNAHAO1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL76793 | 0.77 | HAO1 (0.55) | LMNAHAO1SMN1; SMN2TDP1TP53 | |
| SCHEMBL29411684 | 0.77 | NPC1 (0.50) | LMNAHAO1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345847-B1 | PROCESS FOR THE PREPARATION OF POLYMERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-08-04 | — | — | EP | disclosed |
| US-4965341-A | Polymerization of co/olefin with catalyst comprising sulfur bidentate ligand | SHELL OIL COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0345847-A1 | Process for the preparation of polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-12-13 | — | — | EP | disclosed |