Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.56 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2125126 | 0.83 | MAPT (0.75) | SMN1; SMN2HPGDKMT2AMAPTMEN1 | |
| SCHEMBL9514606 | 0.78 | KMT2A (0.68) | KDM4ESMN1; SMN2HPGDKMT2AMAPT | |
| SCHEMBL2127659 | 0.78 | KMT2A (0.68) | KDM4ESMN1; SMN2HPGDKMT2AMAPT | |
| SCHEMBL2957696 | 0.77 | NOX1 (0.65) | KDM4ESMN1; SMN2HPGDKMT2AMAPT | |
| SCHEMBL5371873 | 0.75 | KDM4E (0.67) | KDM4ESMN1; SMN2HPGDKMT2AMAPT | |
| SCHEMBL7041734 | 0.75 | KDM4E (0.67) | KDM4ESMN1; SMN2HPGDMAPK14MAPK13 | |
| SCHEMBL14023439 | 0.75 | MAPK14 (0.52) | KDM4EHPGDKMT2AMAPTMEN1 | |
| SCHEMBL1068923 | 0.74 | KDM4E (1.00) | KDM4ESMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL31029949 | 0.74 | MAPK14 (0.70) | KMT2AMAPTMEN1RAB9AALDH1A1 | |
| SCHEMBL12561646 | 0.73 | MAPK14 (0.53) | KDM4EHPGDKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365907-B1 | Process for the preparation of p-nitrophenyl imidazoles | BASF AG (DE) | 1993-12-22 | — | — | EP | disclosed |
| US-5008398-A | Preparation of p-nitrophenyl-imidazoles | BASF AKTIENGESELLSCHAFT (DE) | 1991-04-16 | — | — | US | disclosed |
| EP-0365907-A1 | Process for the preparation of p-nitrophenyl imidazoles | BASF Aktiengesellschaft (DE) | 1990-05-02 | — | — | EP | disclosed |