Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.61 |
| ▸ | BCL2L1 | Q07817 | 8/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 8/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515759 | 0.90 | P4HTM (0.58) | P4HTMBCL2L1MCL1EGFR | |
| SCHEMBL9515532 | 0.88 | P4HTM (0.61) | P4HTMBCL2L1MCL1PTGS2PTGS1 | |
| SCHEMBL9516970 | 0.88 | BCL2L1 (0.48) | P4HTMBCL2L1MCL1EGFR | |
| SCHEMBL9517172 | 0.87 | BCL2L1 (0.50) | P4HTMBCL2L1MCL1 | |
| SCHEMBL9517291 | 0.86 | BCL2L1 (0.47) | P4HTMBCL2L1MCL1 | |
| SCHEMBL9517308 | 0.86 | ALDH1A1 (0.50) | P4HTMBCL2L1MCL1 | |
| SCHEMBL9517110 | 0.83 | P4HTM (0.61) | P4HTMBCL2L1MCL1PTGS2PTGS1 | |
| SCHEMBL9517241 | 0.83 | P4HTM (0.61) | P4HTMBCL2L1MCL1PTGS2PTGS1 | |
| SCHEMBL9519602 | 0.82 | ALKBH2 (0.53) | P4HTMBCL2L1MCL1PTGS2PTGS1 | |
| SCHEMBL9517200 | 0.82 | P4HTM (0.70) | P4HTMBCL2L1MCL1PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1079466-A | 4-or 5-(sulphur) acylimino-and (inferior sulphur) amidopyridine and pyridine-N-oxide thereof | HOECHST AG (DE) | 1993-12-15 | — | — | CN | disclosed |
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |