Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12462788 | 0.83 | CDC7 (0.44) | CDC7DAOKDM4EALDH1A1 | |
| SCHEMBL24352160 | 0.81 | GPR84 (0.38) | CDC7MAPTPPARGKDM4EFFAR1 | |
| SCHEMBL9490397 | 0.77 | NOS1 (0.52) | HPGD | |
| SCHEMBL2619120 | 0.74 | CA12 (0.55) | MAPTHPGDDAOKDM4EALDH1A1 | |
| SCHEMBL242258 | 0.74 | MEN1 (0.52) | MAPTHPGDHTTKDM4EALDH1A1 | |
| SCHEMBL6883082 | 0.74 | DAO (0.50) | MAPTHPGDHTTDAOKDM4E | |
| SCHEMBL4618647 | 0.74 | NOS1 (0.52) | MAPK1MAPTDAO | |
| SCHEMBL9490480 | 0.74 | F11 (0.55) | MAPTDAOKDM4EALDH1A1 | |
| SCHEMBL15230239 | 0.74 | CA12 (0.55) | MAPK1MAPTPKM | |
| SCHEMBL28427389 | 0.74 | FLT3 (0.49) | DAOGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284338-B1 | Anti-tumour agents | ICI PLC (GB) | 1993-12-22 | — | — | EP | disclosed |
| US-4981856-A | QUINAZOLINE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-01 | — | — | US | disclosed |
| EP-0284338-A2 | Anti-tumour agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-28 | — | — | EP | disclosed |