Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566768 | 0.90 | P4HTM (0.46) | P4HTMNPC1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9566787 | 0.90 | P4HTM (0.53) | P4HTMNPC1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9566780 | 0.88 | KMT2A (0.45) | P4HTMNPC1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9566771 | 0.88 | P4HTM (0.44) | P4HTMNPC1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9566855 | 0.87 | RAB9A (0.50) | P4HTMNPC1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL9566747 | 0.87 | P4HTM (0.44) | P4HTMNPC1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9566832 | 0.86 | ABL1 (0.48) | P4HTMNPC1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9566825 | 0.85 | P4HTM (0.66) | P4HTMNPC1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9516113 | 0.85 | P4HTM (0.44) | P4HTMNPC1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL9566868 | 0.81 | CXCR2 (0.60) | P4HTMNPC1ALDH1A1RAB9ACXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |