Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519746 | 0.92 | P4HTM (0.40) | P4HTMPOLBCASP3KDM4EALDH1A1 | |
| SCHEMBL9519297 | 0.92 | P4HTM (0.42) | P4HTMPOLBCASP3KDM4EALDH1A1 | |
| SCHEMBL9517204 | 0.89 | P4HTM (0.43) | P4HTMPOLBCASP3KDM4EALDH1A1 | |
| SCHEMBL9516273 | 0.83 | P4HTM (0.41) | P4HTMPOLBKDM4EALDH1A1GAA | |
| SCHEMBL9515669 | 0.83 | LMNA (0.38) | P4HTMPOLBCASP3KDM4ENPC1 | |
| SCHEMBL9515607 | 0.82 | EPHX2 (0.40) | P4HTMCASP3GABRA5 | |
| SCHEMBL9517259 | 0.80 | EGFR (0.39) | P4HTMCASP3GABRA5 | |
| SCHEMBL9515946 | 0.80 | P4HTM (0.40) | P4HTMPOLBCASP3KDM4EALDH1A1 | |
| SCHEMBL9517314 | 0.79 | P4HTM (0.36) | P4HTMCASP3 | |
| SCHEMBL9519643 | 0.79 | GRM5 (0.39) | P4HTMCASP3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |