Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 7/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517259 | 0.91 | EGFR (0.39) | P4HTMCASP3SCN9AEGFRSCN5A | |
| SCHEMBL9516990 | 0.89 | P4HTM (0.37) | P4HTMCASP3SCN9AEGFRSCN5A | |
| SCHEMBL9515748 | 0.87 | P4HTM (0.39) | P4HTMCASP3SCN9AEGFRHDAC6 | |
| SCHEMBL9515607 | 0.85 | EPHX2 (0.40) | P4HTMCASP3HDAC6EPHX2 | |
| SCHEMBL9519643 | 0.84 | GRM5 (0.39) | P4HTMCASP3HDAC6 | |
| SCHEMBL9519628 | 0.84 | BCL2L1 (0.42) | P4HTMCASP3HDAC6 | |
| SCHEMBL9517222 | 0.83 | TRPM8 (0.38) | P4HTMCASP3SCN9ASCN5AHDAC6 | |
| SCHEMBL9517321 | 0.82 | SCN9A (0.37) | P4HTMSCN9AEGFRSCN5AHDAC6 | |
| SCHEMBL9517963 | 0.82 | TLR4 (0.38) | — | |
| SCHEMBL9519634 | 0.82 | HDAC1 (0.39) | CASP3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |