Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | TPMT | P51580 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3609114 | 0.90 | TSHR (0.62) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL14672687 | 0.87 | TOP2A (0.61) | TSHRALDH1A1ALOX15CA12CA1 | |
| SCHEMBL109694 | 0.87 | TOP2A (0.61) | TSHRALDH1A1ALOX15CA12CA1 | |
| SCHEMBL1740685 | 0.87 | ALOX15 (0.53) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL1740674 | 0.87 | ALOX15 (0.53) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL11284887 | 0.86 | ALOX15 (0.55) | KDM4ERAB9AMEN1RECQLKMT2A | |
| SCHEMBL9512855 | 0.85 | ALOX15 (0.53) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL4263896 | 0.84 | ALOX15 (0.52) | TSHRKDM4EALDH1A1MEN1RECQL | |
| SCHEMBL6763903 | 0.83 | KMT2A (0.55) | KDM4EMEN1RECQLKMT2AALOX15 | |
| SCHEMBL1977070 | 0.82 | MGLL (0.52) | TSHRKDM4EALDH1A1MEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308977-B1 | Anthracycline derivatives having inhibitory activity against reverse transcriptase of human immunodeficiency virus | ZAIDAN HOJIN BISEIBUTSU (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5003055-A | Anthracycline derivatives having inhibitory activity against reverse transcriptase of human immunodeficiency virus | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1991-03-26 | — | — | US | disclosed |
| EP-0308977-A2 | Anthracycline derivatives having inhibitory activity against reverse transcriptase of human immunodeficiency virus | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1989-03-29 | — | — | EP | disclosed |