Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.53 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.53 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.53 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 3/20 | 0.47 |
| ▸ | F3 | P13726 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1740685 | 1.00 | ALOX15 (0.53) | ALOX15POLMPOLKPOLLPOLH | |
| SCHEMBL15668298 | 0.89 | ALOX15 (0.52) | ALOX15POLMPOLKPOLLPOLH | |
| SCHEMBL9516469 | 0.87 | TSHR (0.58) | ALOX15TOP2AALDH1A1KDM4ETSHR | |
| SCHEMBL109694 | 0.86 | TOP2A (0.61) | ALOX15TOP2AALDH1A1TSHRHPGD | |
| SCHEMBL14672687 | 0.86 | TOP2A (0.61) | ALOX15TOP2AALDH1A1TSHRHPGD | |
| SCHEMBL31454171 | 0.84 | ALDH1A1 (0.52) | ALOX15POLMPOLKPOLLPOLH | |
| Ammonia Solution, Strong SCHEMBL15285855 | 0.84 | ALOX15 (0.54) | ALOX15POLMPOLKPOLLPOLH | |
| SCHEMBL18481221 | 0.83 | TP53 (0.55) | ALOX15ALDH1A1KDM4ETSHRF7 | |
| SCHEMBL11284326 | 0.83 | ALOX15 (0.49) | ALOX15POLMPOLKPOLLPOLH | |
| SCHEMBL11284329 | 0.83 | POLM (0.47) | ALOX15POLMPOLKPOLLPOLH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389156-A1 | PEG-LIPID CONJUGATES FOR INCREASING THE SOLUBILITY OF DRUG COMPOUNDS | Keller, Brian Charles (US) | 2011-11-30 | — | — | EP | disclosed |
| US-8041911-B2 | Remote copy system and method of deciding recovery point objective in remote copy system | HITACHI, LTD. (JP) | 2011-10-18 | — | — | US | disclosed |
| US-20100210518-A1 | Peg-lipid conjugates for increasing the solubility of drug compounds | KELLER BRIAN CHARLES | 2010-08-19 | — | — | US | disclosed |
| WO-2010085347-A1 | PEG-LIPID CONJUGATES FOR ICREASING THE SOLUBILITY OF DRUG COMPOUNDS | KELLER BRIAN CHARLES (US) | 2010-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210518-A1 | Peg-lipid conjugates for increasing the solubility of drug compounds | LIPA, DAGLA, MGLL | ALOX15 430/4885POLM 2510/4885POLK 2756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.