Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | EBP | Q15125 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3654013 | 0.78 | ESR1 (0.53) | ESR1CYP19A1CYP11B2EBPSIGMAR1 | |
| SCHEMBL10470879 | 0.77 | MIF (0.48) | MIFESR1CYP19A1ALDH1A1MAPT | |
| SCHEMBL3141978 | 0.76 | MPO (0.54) | MIFCYP19A1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7628081 | 0.76 | ESR1 (0.63) | MIFESR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28448661 | 0.75 | ESR2 (0.47) | MIFESR1CYP26A1 | |
| SCHEMBL9516552 | 0.74 | EGFR (0.50) | ESR1CYP19A1ALDH1A1MAPTLMNA | |
| SCHEMBL9516797 | 0.74 | KDM4E (0.47) | MIFESR1CYP19A1ALDH1A1MAPT | |
| SCHEMBL3862097 | 0.74 | ESR1 (0.52) | ESR1ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL17108416 | 0.74 | MPO (0.59) | MIFCYP19A1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7623247 | 0.73 | ESR1 (0.75) | MIFESR1CYP26A1EBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394194-B1 | PROTECTED AMINO-ACIDS AND PROCESS FOR THEIR PREPARATION | CALBIOCHEM-NOVABIOCHEM AG (CH) | 1993-08-18 | — | — | EP | claimed |
| CN-107406424-B | Estrogen receptor modulators and uses thereof | 豪夫迈·罗氏有限公司 | 2020-08-25 | — | — | CN | disclosed |
| EP-0281283-B1 | HETEROCYCLIC COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-10 | — | — | EP | disclosed |
| US-4910212-A | Containing 1,2,4-triazole or imidazole ring | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-03-20 | — | — | US | disclosed |
| EP-0281283-A1 | Heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-07 | — | — | EP | disclosed |