Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517918 | 0.91 | GABRA5 (0.43) | GABRA5PTPN1P4HTMGAAHPGD | |
| SCHEMBL9517019 | 0.89 | GABRA5 (0.40) | GABRA5P4HTMHPGDHDAC6SCN9A | |
| SCHEMBL9516196 | 0.88 | GABRA5 (0.50) | GABRA5PTPN1P4HTMKDM4EALDH1A1 | |
| SCHEMBL9516040 | 0.88 | GABRA5 (0.41) | GABRA5PTPN1P4HTMALDH1A1SMN1; SMN2 | |
| SCHEMBL9517881 | 0.88 | GABRA5 (0.53) | GABRA5PTPN1P4HTMHDAC8HDAC6 | |
| SCHEMBL9516300 | 0.85 | GABRA5 (0.48) | GABRA5PTPN1P4HTMKDM4EALDH1A1 | |
| SCHEMBL9516209 | 0.84 | P4HTM (0.38) | GABRA5P4HTMALDH1A1MAPTHDAC6 | |
| SCHEMBL9516086 | 0.84 | GABRA5 (0.41) | GABRA5PTPN1P4HTMHPGDSMN1; SMN2 | |
| SCHEMBL9519237 | 0.84 | P4HTM (0.55) | P4HTMHDAC6SCN9A | |
| SCHEMBL9517219 | 0.83 | GABRA5 (0.38) | GABRA5ALDH1A1GAAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |