Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27535791 | 0.86 | P4HTM (0.57) | P4HTMCASP3SCN9ASCN5A | |
| SCHEMBL9517019 | 0.85 | GABRA5 (0.40) | P4HTMSCN9ASCN5AHDAC1HDAC6 | |
| SCHEMBL9516888 | 0.84 | GABRA5 (0.50) | P4HTMSCN9AHDAC6 | |
| SCHEMBL9515532 | 0.84 | P4HTM (0.61) | P4HTMCASP3 | |
| SCHEMBL9519164 | 0.81 | P4HTM (0.61) | P4HTMCASP3SCN9ASCN5ASCN3A | |
| SCHEMBL9515461 | 0.81 | P4HTM (0.62) | P4HTMHDAC1HDAC6 | |
| SCHEMBL9517918 | 0.80 | GABRA5 (0.43) | P4HTMSCN9ASCN5A | |
| SCHEMBL9516209 | 0.80 | P4HTM (0.38) | P4HTMSCN9ASCN5AHDAC6 | |
| SCHEMBL9517975 | 0.80 | P4HTM (0.53) | P4HTMCASP3SCN9ASCN3A | |
| SCHEMBL18961357 | 0.79 | MAPT (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |