Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5199349 | 0.75 | PNP (0.36) | KDM4ELMNAMAPT | |
| SCHEMBL6546417 | 0.75 | ALDH1A1 (0.47) | KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL29484715 | 0.74 | NOTUM (0.45) | NOTUMLRRK2DDB1CRBNAR | |
| SCHEMBL8863558 | 0.74 | NOTUM (0.45) | NOTUMLRRK2DDB1CRBNAR | |
| SCHEMBL9304520 | 0.72 | AR (0.42) | ARMAPT | |
| SCHEMBL11561262 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL452473 | 0.70 | ALDH1A1 (0.35) | NOTUMKDM4ELMNAMAPTNPSR1 | |
| SCHEMBL6546558 | 0.69 | SIRT1 (0.35) | — | |
| SCHEMBL10841901 | 0.69 | PDE7A (0.50) | KDM4ELMNAMAPT | |
| SCHEMBL6552282 | 0.68 | ALDH1A1 (0.34) | NOTUMLMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315114-B1 | Silver halide color photographic light-sensitive material | MINNESOTA MINING & MFG (US) | 1993-12-15 | — | — | EP | disclosed |
| US-4908302-A | Support, silver halide emulsion containing diketomethylene yellow dye forming coupler and development inhibitor | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-03-13 | — | — | US | disclosed |
| EP-0315114-A2 | Silver halide color photographic light-sensitive material | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-05-10 | — | — | EP | disclosed |