SCHEMBL6546558

SCHEMBL6546558

NC(=S)c1ccccc1Sc1nnn[nH]1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SIRT1 Q96EB6 1/20 0.35
PRKAG1 P54619 1/20 0.31
PRKAA2 P54646 1/20 0.31
PRKAB1 Q9Y478 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9670035 0.79 PRKAG1 (0.36) SIRT1PRKAG1PRKAA2PRKAB1
SCHEMBL5199349 0.76 PNP (0.36)
SCHEMBL6546417 0.76 ALDH1A1 (0.47)
SCHEMBL2712364 0.75 CES2 (0.39) SIRT1PRKAG1PRKAA2PRKAB1
SCHEMBL10703572 0.74 TDP1 (0.39)
SCHEMBL11561262 0.69 ALDH1A1 (0.32)
SCHEMBL9517036 0.69 NOTUM (0.40)
SCHEMBL452473 0.68 ALDH1A1 (0.35)
SCHEMBL5162072 0.67 ALDH1A1 (0.44)
SCHEMBL10841901 0.67 PDE7A (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893731-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK CO (US) 2004-01-28 EP disclosed
US-6498004-B1 FRAGMENTABLE TWO-ELECTRON DONOR COMPOUNDS THAT ARE ATTACHED TO A PROTECTIVE GROUP WHEREIN SUCH PROTECTIVE GROUP IS ELIMINATED DURING DEVELOPMENT TO GIVE THE FRAGMENTABLE ELECTRON DONOR; WITHOUT AN INCREASE IN FOG EASTMAN KODAK COMPANY 2002-12-24 US disclosed
EP-1220024-A2 Silver halide photographic element EASTMAN KODAK COMPANY (US) 2002-07-03 EP disclosed
US-6306570-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY 2001-10-23 US disclosed
US-6054260-A Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 2000-04-25 US disclosed
EP-0893731-A1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 1999-01-27 EP disclosed