Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 7/20 | 0.43 |
| ▸ | FLT4 | P35916 | 7/20 | 0.43 |
| ▸ | KDR | P35968 | 7/20 | 0.43 |
| ▸ | CA2 | P00918 | 7/20 | 0.36 |
| ▸ | CA1 | P00915 | 6/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20449115 | 0.85 | CA12 (0.44) | FLT1FLT4KDRCA2CA1 | |
| SCHEMBL17094979 | 0.85 | HSD17B10 (0.43) | FLT1FLT4KDRCA2CA1 | |
| SCHEMBL1259363 | 0.84 | LMNA (0.49) | FLT1FLT4KDRCA2CA1 | |
| SCHEMBL7993462 | 0.82 | ALDH1A1 (0.38) | FLT1FLT4KDRHSD17B10ALDH1A1 | |
| SCHEMBL16908460 | 0.80 | ALDH1A1 (0.43) | FLT1FLT4KDRCA2CA1 | |
| SCHEMBL3163226 | 0.79 | FLT1 (0.43) | FLT1FLT4KDRGPR27AVPR2 | |
| SCHEMBL28174295 | 0.76 | CA1 (0.33) | FLT1FLT4KDRCA2CA1 | |
| SCHEMBL3194901 | 0.76 | CA2 (0.43) | FLT1FLT4KDRCA2CA1 | |
| SCHEMBL397333 | 0.76 | LMNA (0.51) | FLT1FLT4KDRALDH1A1 | |
| SCHEMBL11222667 | 0.76 | ALDH1A1 (0.49) | CA2CA1CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447421-B1 | PREPARATION OF 2-(CHLORO, BROMO OR NITRO)-4-(ALKYLSULFONYL)BENZOIC ACIDS AND INTERMEDIATES | ZENECA INC (US) | 1993-12-15 | — | — | EP | disclosed |
| US-5157150-A | Preparation of 2-(chloro, bromo or nitro)-4-(alkylsulfonyl)benzoic acids and intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-20 | — | — | US | disclosed |
| US-5008448-A | Preparation of 2-(chloro, bromo or nitro)-4-(alkyl-sulfonyl)benzoic acids and intermediates | ICI AMERICAS INC. (US) | 1991-04-16 | — | — | US | disclosed |
| WO-1990006301-A1 | PREPARATION OF 2-(CHLORO, BROMO OR NITRO)-4-(ALKYLSULFONYL)BENZOIC ACIDS AND INTERMEDIATES | ICI AMERICAS INC. (US) | 1990-06-14 | — | — | WO | disclosed |