SCHEMBL7993462

SCHEMBL7993462

O=C(Cl)c1ccc(S(=O)(=O)Cl)cc1C(=O)Cl

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
HSD17B10 Q99714 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
LMNA P02545 1/20 0.38
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.35
FLT1 P17948 8/20 0.34
FLT4 P35916 8/20 0.34
KDR P35968 8/20 0.34
ALOX15 P16050 1/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KMT2A Q03164 1/20 0.32
MAOB P27338 1/20 0.32
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3163226 0.84 FLT1 (0.43) LMNAKDM4EFLT1FLT4KDR
SCHEMBL11222667 0.84 ALDH1A1 (0.49) ALDH1A1HSD17B10TDP1LMNAKDM4E
SCHEMBL397333 0.84 LMNA (0.51) ALDH1A1LMNAFLT1FLT4KDR
SCHEMBL9517136 0.82 FLT1 (0.43) ALDH1A1HSD17B10TDP1FLT1FLT4
SCHEMBL12569837 0.82 ALDH1A1 (0.47) ALDH1A1HSD17B10LMNAKDM4EHPGD
SCHEMBL17094979 0.82 HSD17B10 (0.43) ALDH1A1HSD17B10TDP1LMNAKDM4E
SCHEMBL15575808 0.82 LMNA (0.39) ALDH1A1TDP1LMNAKDM4EFLT1
SCHEMBL11582938 0.79 L3MBTL1 (0.50) ALDH1A1HSD17B10TDP1LMNAKDM4E
SCHEMBL9517119 0.78 FLT1 (0.47) ALDH1A1TDP1HPGDFLT1FLT4
SCHEMBL31042237 0.78 GAA (0.47) LMNAFLT1FLT4KDRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0227043-A2 Composite semipermeable membrane and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-07-01 EP claimed
CN-102718690-A Polyvinyl chloride plasticizer and preparation method thereof UNIV FUDAN 2012-10-10 CN disclosed
WO-2001010838-A1 MULTIVALENT COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2001-02-15 WO disclosed
EP-0227043-A2 Composite semipermeable membrane and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-07-01 EP disclosed
EP-0061013-B1 PROCESS FOR THE PREPARATION OF POLYISOCYANATES BAYER AG (DE) 1984-06-27 EP disclosed
US-4388246-A THERMAL SPLITTING OF CARBAMATES BAYER AKTIENGESELLSCHAFT (DE) 1983-06-14 US disclosed
EP-0061013-A1 Process for the preparation of polyisocyanates BAYER AG (DE) 1982-09-29 EP disclosed