SCHEMBL9517185

SCHEMBL9517185

Clc1cc2ccccn2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.48
RAB9A P51151 8/20 0.47
NPC1 O15118 7/20 0.47
ALDH1A1 P00352 6/20 0.47
MAPT P10636 5/20 0.47
SMN1; SMN2 Q16637 4/20 0.47
KDM4E B2RXH2 4/20 0.47
POLB P06746 3/20 0.47
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
MAPK1 P28482 2/20 0.34
CHRNA7 P36544 1/20 0.34
HRH3 Q9Y5N1 3/20 0.33
SSTR4 P31391 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29089761 0.78 ALDH1A1 (0.62) ALOX15RAB9ANPC1ALDH1A1MAPT
SCHEMBL7073890 0.74 ALOX15 (0.50) ALOX15RAB9ANPC1ALDH1A1MAPT
SCHEMBL20955977 0.74 ALOX15 (0.50) ALOX15RAB9ANPC1ALDH1A1MAPT
SCHEMBL15683854 0.73 ALOX15 (0.48) ALOX15RAB9ANPC1ALDH1A1MAPT
SCHEMBL10123564 0.73 ALOX15 (0.48) ALOX15RAB9ANPC1ALDH1A1MAPT
SCHEMBL2010683 0.73 ALOX15 (0.48) ALOX15RAB9ANPC1ALDH1A1MAPT
SCHEMBL277387 0.73 ALOX15 (0.48) ALOX15RAB9ANPC1ALDH1A1MAPT
SCHEMBL21824311 0.73 ALOX15 (0.48) ALOX15RAB9ANPC1ALDH1A1MAPT
SCHEMBL321553 0.73 ALOX15 (0.48) ALOX15RAB9ANPC1ALDH1A1MAPT
SCHEMBL1646529 0.72 ALDH1A1 (0.51) ALOX15RAB9ANPC1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1026048-C Use of solsonylurea compounds as herbicide TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1994-10-05 CN disclosed
EP-0238070-B1 Sulfonylurea compounds, their production and herbicidal use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-29 EP disclosed
CN-1018643-B Process for producing sulfonylurea compound TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1992-10-14 CN disclosed
CN-1059073-A Solsonylurea compounds is as the purposes of weed killer herbicide TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1992-03-04 CN disclosed
US-5017212-A For rice paddies TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-05-21 US disclosed
CN-87102123-A Sulfonylurea compounds, their preparation and their use as herbicides 1987-10-21 CN disclosed
EP-0238070-A2 Sulfonylurea compounds, their production and herbicidal use Takeda Chemical Industries, Ltd. (JP) 1987-09-23 EP disclosed