Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Dichloroethane SCHEMBL27922038 | 0.90 | NPC1 (0.41) | ALOX15NPC1RAB9AALDH1A1SMN1; SMN2 | |
| Thiophene SCHEMBL28091067 | 0.89 | NPC1 (0.40) | ALOX15NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL873426 | 0.78 | ALDH1A1 (0.62) | ALOX15NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4796310 | 0.77 | ALOX15 (0.44) | ALOX15NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL149606 | 0.76 | NPC1 (0.51) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL22515602 | 0.76 | ALOX15 (0.46) | ALOX15NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL3884828 | 0.75 | SMN1; SMN2 (0.58) | ALOX15NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4566860 | 0.74 | ALOX15 (0.50) | ALOX15NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4566858 | 0.74 | ALOX15 (0.50) | ALOX15NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL22427645 | 0.74 | ALOX15 (0.35) | ALOX15NPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6572664-B2 | Oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2003-06-03 | — | — | US | claimed |
| US-20020170121-A9 | Indolizine derivatives, compositions comprising at least one coupler chosen from indolizine derivatives and at least one oxidation base, and methods for using same | L'OREAL S.A. (FR) | 2002-11-21 | — | — | US | claimed |
| US-20020002749-A1 | Indolizine derivatives, compositions comprising at least one coupler chosen from indolizine derivatives and at least one oxidation base, and methods for using same | BRETON PHILIPPE (FR) | 2002-01-10 | — | — | US | claimed |
| EP-1129691-A2 | Compositions for dyeing keratinous fibers containing indolizine derivatives and dyeing method using same | L'OREAL (FR) | 2001-09-05 | — | — | EP | claimed |
| US-5134239-A | Quaterinary indolizine compound | THE DOW CHEMICAL COMPANY (US) | 1992-07-28 | — | — | US | claimed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | claimed |
| US-12202829-B2 | Heterocyclic compound | FIMECS, INC. (JP) | 2025-01-21 | — | — | US | disclosed |
| US-20240327410-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2024-10-03 | — | — | US | disclosed |
| US-11993601-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV | 2024-05-28 | — | — | US | disclosed |
| US-20240025906-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | SUNDANCE BIOSCIENCES, INC. | 2024-01-25 | — | — | US | disclosed |
| EP-4306166-A2 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | Aquinnah Pharmaceuticals Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| WO-2023249872-A1 | SUBSTITUTED FUSED BICYCLIC COMPOUNDS AND RELATED METHODS OF TREATMENT | ALKERMES, INC. (US) | 2023-12-28 | — | — | WO | disclosed |
| EP-4289813-A2 | INTERMEDIATES TO OBTAIN SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | Global Blood Therapeutics, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| EP-0026859-B1 | IMAGE-FORMING PHOTOSENSITIVE COMPOSITION, PHOTOSENSITIVE COATING SOLUTION AND PHOTOSENSITIVE SHEET COMPRISING THIS COMPOSITION | ORIENTAL PHOTO INDUSTRIES, CO., LTD. (JP) | 1983-10-05 | — | — | EP | disclosed |
| US-4400387-A | USEFUL IN VETERINARY MEDICINE FOR TREATMENT OF PSYCHOLOGICAL DISORDERS | S. A. LABAZ-SANOFI N.V. (FR) | 1983-08-23 | — | — | US | disclosed |
| EP-0000082-B1 | PROCESS FOR IMAGE-WISE MODIFYING THE SURFACE OF AN ETCHABLE SUPPORT AND MATERIAL SUITABLE THEREFOR COMPRISING A COLLOID LAYER CONTAINING POLYMERS WITH OXIME-ESTER GROUPS | AGFA-GEVAERT N.V. (BE) | 1982-07-21 | — | — | EP | disclosed |
| EP-0026859-A2 | Image-forming photosensitive composition, photosensitive coating solution and photosensitive sheet comprising this composition | ORIENTAL PHOTO INDUSTRIES, CO., LTD. (JP) | 1981-04-15 | — | — | EP | disclosed |
| US-4202697-A | Production of etch-resist colloid and material suitable therefor | AGFA-GEVAERT N.V. (BE) | 1980-05-13 | — | — | US | disclosed |
| EP-0000082-A1 | Process for image-wise modifying the surface of an etchable support and material suitable therefor comprising a colloid layer containing polymers with oxime-ester groups | AGFA-GEVAERT N.V. (BE) | 1978-12-20 | — | — | EP | disclosed |
| US-4103012-A | CARDIOVASCULAR DISORDERS | LABAZ (FR) | 1978-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020002749-A1 | Indolizine derivatives, compositions comprising at least one coupler chosen from indolizine derivatives and at least one oxidation base, and methods for using same | KRT18, INMT, IDO1 | ALOX15 1936/4885NPC1 4832/4885RAB9A 4574/4885 |
| US-20020170121-A9 | Indolizine derivatives, compositions comprising at least one coupler chosen from indolizine derivatives and at least one oxidation base, and methods for using same | KRT18, INMT, IDO1 | ALOX15 1936/4885NPC1 4832/4885RAB9A 4574/4885 |
| US-11993601-B2 | Monoacylglycerol lipase modulators | MGLL, LPL, PNLIP | ALOX15 157/4885NPC1 826/4885RAB9A 994/4885 |
| US-20240327410-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | ALOX15 157/4885NPC1 826/4885RAB9A 994/4885 |
| US-12202829-B2 | Heterocyclic compound | XIAP, BIRC5, BIRC3 | ALOX15 3474/4885NPC1 2963/4885RAB9A 2828/4885 |
| US-20240025906-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | TYK2, JAK1, JAK3 | ALOX15 3189/4885NPC1 4600/4885RAB9A 3465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.