Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517201 | 0.93 | TSHR (0.52) | ALDH1A1TSHRCNR2CYSLTR1 | |
| SCHEMBL9515903 | 0.86 | NPC1 (0.51) | LMNASMN1; SMN2ALDH1A1KMT2ACYSLTR1 | |
| SCHEMBL9519208 | 0.85 | P4HTM (0.39) | LMNAALDH1A1KMT2ACYSLTR1 | |
| SCHEMBL9516791 | 0.84 | LMNA (0.54) | LMNASMN1; SMN2ALDH1A1TDP1NPSR1 | |
| SCHEMBL9516933 | 0.83 | CNR2 (0.51) | LMNASMN1; SMN2ALDH1A1TDP1NPSR1 | |
| SCHEMBL9515556 | 0.83 | CNR2 (0.51) | LMNASMN1; SMN2ALDH1A1TDP1NPSR1 | |
| SCHEMBL9515933 | 0.81 | P4HTM (0.55) | ALDH1A1TSHRKMT2A | |
| SCHEMBL9517969 | 0.80 | EPHX2 (0.44) | LMNASMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL8868704 | 0.77 | P4HTM (0.48) | LMNASMN1; SMN2ALDH1A1TSHRKMT2A | |
| SCHEMBL9516064 | 0.77 | TSHR (0.62) | ALDH1A1TSHRKMT2ACNR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |