Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5676415 | 0.83 | GABRA1 (0.54) | GABRA1GABRB2TYRTRPA1ESR1 | |
| SCHEMBL11576459 | 0.83 | HTR1D (0.40) | TYRTRPA1ATMPOLBRECQL | |
| SCHEMBL5709273 | 0.82 | TYR (0.52) | GABRA1GABRB2TYRTRPA1ATM | |
| SCHEMBL70108 | 0.81 | TYR (0.60) | GABRA1GABRB2TYRTRPA1ATM | |
| SCHEMBL31620170 | 0.81 | GABRA1 (0.46) | GABRA1GABRB2TYRTRPA1RECQL | |
| SCHEMBL7623340 | 0.81 | GABRA1 (0.46) | GABRA1GABRB2TYRTRPA1RECQL | |
| SCHEMBL27362377 | 0.81 | SHBG (0.42) | TYRTRPA1ATMPOLBRECQL | |
| SCHEMBL18904546 | 0.80 | AMY1A (0.50) | GABRA1GABRB2TYRPOLBRECQL | |
| SCHEMBL15655659 | 0.79 | PON1 (0.40) | GABRA1GABRB2TYRTRPA1ATM | |
| SCHEMBL13057531 | 0.79 | GABRA1 (0.50) | GABRA1GABRB2TYRPOLBNQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101062880-A | Ethylene device quench oil viscosity reductant | CHINA PETROLEUM & CHEMICAL (CN) | 2007-10-31 | — | — | CN | claimed |
| EP-0130839-B1 | THERMOPLASTIC RESIN AND A BLENDED COMPOSITION INCORPORATING THE SAME | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1990-05-02 | — | — | EP | claimed |
| US-4742115-A | POLYPHENYLENE THER, ACRYLONITRILE-STYRENIC COPOLYMER | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1988-05-03 | — | — | US | claimed |
| EP-0130839-A2 | Thermoplastic resin and a blended composition incorporating the same | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1985-01-09 | — | — | EP | claimed |
| WO-2023162552-A1 | CHEMICALLY AMPLIFIED POSITIVE PHOTOSENSITIVE COMPOSITION, PRODUCTION METHOD FOR SUBSTRATE WITH TEMPLATE, AND PRODUCTION METHOD FOR PLATED ARTICLE | 東京応化工業株式会社 | 2023-08-31 | — | — | WO | disclosed |
| US-20230132823-A1 | BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR | DBD THERAPEUTICS, LLC | 2023-05-04 | — | — | US | disclosed |
| US-20170355849-A1 | NOVEL EPOXY NOVOLAC COMPOSITES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-12-14 | — | — | US | disclosed |
| US-9663508-B2 | Biaryl acyl-sulfonamide compounds as sodium channel inhibitors | AMGEN INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-9663508-B2 | Biaryl acyl-sulfonamide compounds as sodium channel inhibitors | AMGEN INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160214971-A1 | Biaryl Acyl-Sulfonamide Compounds as Sodium Channel Inhibitors | One Amgen Center Drive (US) | 2016-07-28 | — | — | US | disclosed |
| US-20160214971-A1 | Biaryl Acyl-Sulfonamide Compounds as Sodium Channel Inhibitors | One Amgen Center Drive (US) | 2016-07-28 | — | — | US | disclosed |
| WO-2015051043-A1 | BIARYL ACYL-SULFONAMIDE COMPOUNDS AS SODIUM CHANNEL INHIBITORS | AMGEN INC. (US) | 2015-04-09 | — | — | WO | disclosed |
| EP-0360544-A2 | Thermoplastic resinous composition | UBE INDUSTRIES, LTD. (JP) | 1990-03-28 | — | — | EP | disclosed |
| US-4873133-A | LAMINATED FIBER MAT HAS LONG FIBERS PENETRATING SUPPORT FILM | GENERAL ELECTRIC COMPANY (US) | 1989-10-10 | — | — | US | disclosed |
| US-4742115-A | POLYPHENYLENE THER, ACRYLONITRILE-STYRENIC COPOLYMER | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0259676-A2 | Fiber reinforced stampable thermoplastic sheet | GENERAL ELECTRIC COMPANY (US) | 1988-03-16 | — | — | EP | disclosed |
| EP-0199510-A2 | Polyphenylene ether resin composition | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1986-10-29 | — | — | EP | disclosed |
| US-4560808-A | CATALYTIC TRANSALKYLATION OF MONOHYDROXY AROMATIC WITH DIHYDROXY COMPOUND | GENERAL ELECTRIC COMPANY (US) | 1985-12-24 | — | — | US | disclosed |
| EP-0130839-A2 | Thermoplastic resin and a blended composition incorporating the same | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1985-01-09 | — | — | EP | disclosed |
| US-4038343-A | RESIN COMPOSITION CONTAINING COPOLYPHENYLENE ETHER | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) | 1977-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214971-A1 | Biaryl Acyl-Sulfonamide Compounds as Sodium Channel Inhibitors | SCN1A, SCN1B, SCN5A | GABRA1 363/4885GABRB2 450/4885TYR 1897/4885 |
| US-20230132823-A1 | BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR | AR, ADRM1, PSMA3 | GABRA1 307/4885GABRB2 212/4885TYR 4698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.