Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517515 | 1.00 | CYP1A2 (0.42) | CYP1A2CYP2C19ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL17846485 | 0.84 | LIPG (0.55) | LIPGTRPV1 | |
| SCHEMBL21221594 | 0.78 | RAB9A (0.46) | CYP1A2CYP2C19PTGDR2NPC1RAB9A | |
| SCHEMBL734050 | 0.76 | LMNA (0.38) | CYP1A2CYP2C19ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL17846500 | 0.75 | TRPV1 (0.50) | LIPGHPGDTRPV1 | |
| SCHEMBL19033732 | 0.74 | SLC18A3 (0.39) | CYP1A2CYP2C19ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL16543179 | 0.74 | LIPG (0.80) | CYP1A2CYP2C19LIPGPTGDR2NPC1 | |
| SCHEMBL7969531 | 0.73 | ALDH1A1 (0.55) | ALDH1A1LIPGNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7969528 | 0.73 | ALDH1A1 (0.55) | ALDH1A1LIPGNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17296744 | 0.73 | LIPG (0.43) | CYP1A2CYP2C19LIPGPTGDR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559743-A1 | NOVEL HYDROXAMIC ACID AND N-HYDROXYUREA DERIVATIVES AND THEIR USE. | PFIZER HOSPITAL PROD (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1992009566-A1 | NOVEL HYDROXAMIC ACID AND N-HYDROXYUREA DERIVATIVES AND THEIR USE | PFIZER INC. (US) | 1992-06-11 | — | — | WO | disclosed |