SCHEMBL9517530

SCHEMBL9517530

O=P(O)(O)c1ccccc1S(=O)(=O)Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTK2B Q14289 5/20 0.39
POLB P06746 3/20 0.39
NPC1 O15118 2/20 0.39
ALDH1A1 P00352 2/20 0.38
CA2 P00918 2/20 0.38
CA4 P22748 1/20 0.38
CA5A P35218 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
RAB9A P51151 1/20 0.38
ALPG P10696 1/20 0.37
MAPT P10636 1/20 0.36
RXFP1 Q9HBX9 1/20 0.33
KDM4E B2RXH2 1/20 0.33
TRPV4 Q9HBA0 1/20 0.32
CA9 Q16790 2/20 0.32
CA1 P00915 1/20 0.32
CA12 O43570 1/20 0.32
MMP2 P08253 1/20 0.32
CA14 Q9ULX7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL6012154 0.82 PTK2B (0.38) PTK2BPOLBNPC1ALDH1A1CA2
SCHEMBL340555 0.81 PTK2B (0.40) PTK2BPOLBNPC1ALDH1A1CA2
SCHEMBL9943663 0.79 PTK2B (0.39) PTK2BPOLBNPC1ALDH1A1CA2
SCHEMBL9813374 0.79 ELANE (0.42) PTK2BPOLBNPC1ALDH1A1CA2
SCHEMBL8842454 0.75 PTK2B (0.36) PTK2BPOLBNPC1ALDH1A1CA2
SCHEMBL250199 0.74 ALDH1A1 (0.55) ALDH1A1CA2CA4CA5AHSD17B10
SCHEMBL2173729 0.74 CA2 (0.55) PTK2BPOLBNPC1ALDH1A1CA2
SCHEMBL29733396 0.74 CA2 (0.55) PTK2BPOLBNPC1ALDH1A1CA2
Phosphoric Acid SCHEMBL8953318 0.71 PTK2B (0.47) PTK2BPOLBNPC1ALDH1A1CA2
Phosphoric Acid SCHEMBL5534159 0.71 TTR (0.38) PTK2BPOLBNPC1ALDH1A1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0386845-B1 SOLID CATALYST FUNCTIONALIZED WITH SULFONIC GROUPS, PROCESS FOR PREPARING IT AND ITS USE ENIRICERCHE S.p.A. (IT) 1993-08-04 EP disclosed
EP-0386845-A1 Solid catalyst functionalized with sulfonic groups, process for preparing it and its use ENIRICERCHE S.p.A. (IT) 1990-09-12 EP disclosed