Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.31 |
| ▸ | CA1 | P00915 | 5/20 | 0.31 |
| ▸ | CA2 | P00918 | 5/20 | 0.31 |
| ▸ | CA9 | Q16790 | 5/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3171384 | 1.00 | FAAH (0.33) | FAAHALDH1A1TDP1THRBMEN1 | |
| SCHEMBL6857336 | 1.00 | FAAH (0.33) | FAAHALDH1A1TDP1THRBMEN1 | |
| SCHEMBL6608086 | 0.84 | — | — | |
| SCHEMBL27408823 | 0.81 | ALDH1A1 (0.34) | ALDH1A1TDP1THRBMEN1HTT | |
| SCHEMBL13645501 | 0.79 | DUT (0.38) | ALDH1A1TDP1THRBMEN1HTT | |
| SCHEMBL18746891 | 0.79 | DUT (0.38) | ALDH1A1TDP1THRBMEN1HTT | |
| SCHEMBL9671669 | 0.79 | DUT (0.38) | ALDH1A1TDP1THRBMEN1HTT | |
| SCHEMBL8072599 | 0.79 | DUT (0.38) | ALDH1A1TDP1THRBMEN1HTT | |
| SCHEMBL31039441 | 0.79 | DUT (0.38) | ALDH1A1TDP1THRBMEN1HTT | |
| SCHEMBL29928092 | 0.79 | DUT (0.38) | ALDH1A1TDP1THRBMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384842-B1 | 19-Nor steroids substituted at position 11-beta by a hydrocarbon chain containing an amide or carbamate group, their preparation, intermediates, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1993-12-29 | — | — | EP | disclosed |
| EP-0384842-A1 | 19-Nor steroids substituted at position 11-beta by a hydrocarbon chain containing an amide or carbamate group, their preparation, intermediates, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1990-08-29 | — | — | EP | disclosed |