Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10676472 | 0.92 | L3MBTL1 (0.40) | L3MBTL1MAPTCYP2D6TSHRALDH1A1 | |
| SCHEMBL11845836 | 0.74 | TSHR (0.37) | L3MBTL1MAPTCYP2D6TSHRALDH1A1 | |
| SCHEMBL9185214 | 0.71 | GAA (0.41) | L3MBTL1MAPTCYP2D6TSHRALDH1A1 | |
| SCHEMBL9515797 | 0.70 | CHRNB2 (0.34) | L3MBTL1MAPTTSHRALDH1A1ABL1 | |
| SCHEMBL9601913 | 0.69 | ALDH1A1 (0.39) | L3MBTL1MAPTALDH1A1POLBKMT2A | |
| SCHEMBL1917616 | 0.69 | CYP2D6 (0.36) | MAPTCYP2D6ALDH1A1KMT2ANPC1 | |
| SCHEMBL2130385 | 0.69 | ALDH1A1 (0.46) | MAPTCYP2D6ALDH1A1LMNAPOLB | |
| SCHEMBL28351448 | 0.67 | POLB (0.45) | MAPTCYP2D6ALDH1A1POLBKMT2A | |
| SCHEMBL8092424 | 0.67 | ALDH1A1 (0.37) | L3MBTL1MAPTCYP2D6TSHRALDH1A1 | |
| SCHEMBL10654314 | 0.67 | MAPT (0.43) | L3MBTL1MAPTALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538692-A1 | Use of partly known substituted pyrrolidine derivatives as pharmaceuticals, new compounds and process for their preparation | BAYER AG (DE) | 1993-04-28 | — | — | EP | disclosed |