Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518447 | 0.85 | RORC (0.32) | — | |
| SCHEMBL9521480 | 0.83 | TSHR (0.40) | ENPP2 | |
| SCHEMBL10539494 | 0.79 | SIRT2 (0.32) | ENPP2 | |
| SCHEMBL9518474 | 0.79 | ENPP2 (0.32) | ENPP2 | |
| SCHEMBL34464492 | 0.74 | ENPP2 (0.31) | ENPP2 | |
| SCHEMBL31285054 | 0.70 | NR3C1 (0.40) | ENPP2 | |
| SCHEMBL3418683 | 0.70 | KCNN4 (0.40) | ENPP2 | |
| SCHEMBL9521459 | 0.70 | ENPP2 (0.32) | ENPP2 | |
| SCHEMBL9518239 | 0.70 | — | — | |
| SCHEMBL31285478 | 0.69 | ENPP2 (0.36) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269599-B1 | Substituted 1H-imidazoles | UCB SA (BE) | 1993-12-15 | — | — | EP | disclosed |
| EP-0300657-B1 | 4-SUBSTITUTED 3-OXOBUTANOATE ESTER DERIVATIVES | MERCK & CO. INC. (US) | 1993-03-31 | — | — | EP | disclosed |
| US-4814343-A | ANTIISCHEMIC | U C B, S.A. (BE) | 1989-03-21 | — | — | US | disclosed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | disclosed |