Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750922 | 0.86 | HMGCR (0.55) | HMGCRPTGS2ALDH1A1POLBAR | |
| SCHEMBL9521513 | 0.86 | HMGCR (0.55) | HMGCRPTGS2ALDH1A1POLBAR | |
| SCHEMBL9518289 | 0.85 | HMGCR (0.47) | HMGCRPTGS2ALDH1A1POLBLMNA | |
| SCHEMBL4886001 | 0.79 | ALDH1A1 (0.56) | ALDH1A1LMNAAVPR1A | |
| SCHEMBL9750902 | 0.76 | HMGCR (0.46) | HMGCRPTGS2ALDH1A1KDM4ETDP1 | |
| SCHEMBL9750899 | 0.76 | HMGCR (0.46) | HMGCRPTGS2ALDH1A1KDM4ETDP1 | |
| SCHEMBL9764621 | 0.74 | HMGCR (0.41) | HMGCRPTGS2ALDH1A1LMNAAR | |
| SCHEMBL9764105 | 0.74 | MEN1 (0.39) | HMGCRPTGS2ALDH1A1POLBLMNA | |
| SCHEMBL9518489 | 0.73 | HMGCR (0.56) | HMGCRPTGS2ALDH1A1ARTDP1 | |
| SCHEMBL9764185 | 0.73 | KDM4E (0.48) | HMGCRALDH1A1POLBARKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312723-B1 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID CO (US) | 1993-12-22 | — | — | EP | disclosed |
| EP-0300249-B1 | 7-[1H-pyrrol-3-yl]-substituted 3,5-dihydroxy-heptane acids, their corresponding delta-lactones and salts, processes for their manufacture, their use as medicines, pharmaceutical preparations and intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-03 | — | — | EP | disclosed |
| US-5055484-A | Anticholesterol and antilipemic agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |
| EP-0347488-A1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1989-12-27 | — | — | EP | disclosed |