Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.36 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750899 | 0.88 | HMGCR (0.46) | HMGCRALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL9750902 | 0.88 | HMGCR (0.46) | HMGCRALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL9764621 | 0.88 | HMGCR (0.41) | HMGCRALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL9764185 | 0.86 | KDM4E (0.48) | HMGCRALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL9518519 | 0.85 | HMGCR (0.54) | HMGCRALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL9750893 | 0.80 | KDM4E (0.52) | HMGCRALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL9764104 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KDM4ETDP1L3MBTL1PTGS2 | |
| SCHEMBL9764105 | 0.77 | MEN1 (0.39) | HMGCRALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL9518614 | 0.77 | HMGCR (0.48) | HMGCRALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL8805119 | 0.76 | ALDH1A1 (0.40) | ALDH1A1KDM4ETDP1L3MBTL1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239306-B1 | TETRAHYDROCARBAZOLE ESTERS | MERCK FROSST CANADA INC. (CA) | 1993-06-02 | — | — | EP | claimed |
| EP-0300249-B1 | 7-[1H-pyrrol-3-yl]-substituted 3,5-dihydroxy-heptane acids, their corresponding delta-lactones and salts, processes for their manufacture, their use as medicines, pharmaceutical preparations and intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-03 | — | — | EP | disclosed |
| US-5055484-A | Anticholesterol and antilipemic agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |
| EP-0300249-A1 | 7-[1H-pyrrol-3-yl]-substituted 3,5-dihydroxy-heptane acids, their corresponding delta-lactones and salts, processes for their manufacture, their use as medicines, pharmaceutical preparations and intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-25 | — | — | EP | disclosed |