Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521513 | 1.00 | HMGCR (0.55) | HMGCRPTGS2POLBMEN1KMT2A | |
| SCHEMBL9750902 | 0.87 | HMGCR (0.46) | HMGCRPTGS2MEN1KMT2AALDH1A1 | |
| SCHEMBL9750899 | 0.87 | HMGCR (0.46) | HMGCRPTGS2MEN1KMT2AALDH1A1 | |
| SCHEMBL9518519 | 0.86 | HMGCR (0.54) | HMGCRPTGS2POLBALDH1A1KDM4E | |
| SCHEMBL9756864 | 0.77 | HMGCR (0.38) | HMGCRPTGS2MEN1KMT2AALDH1A1 | |
| SCHEMBL9756865 | 0.77 | HMGCR (0.38) | HMGCRPTGS2MEN1KMT2AALDH1A1 | |
| SCHEMBL9518289 | 0.75 | HMGCR (0.47) | HMGCRPTGS2POLBMEN1KMT2A | |
| SCHEMBL9751007 | 0.75 | HMGCR (0.56) | HMGCRPTGS2POLBMEN1KMT2A | |
| SCHEMBL9751002 | 0.75 | HMGCR (0.56) | HMGCRPTGS2POLBMEN1KMT2A | |
| SCHEMBL6962562 | 0.73 | MEN1 (0.41) | HMGCRPTGS2POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055484-A | Anticholesterol and antilipemic agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |