Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | TSPO | P30536 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2107224 | 0.90 | ALDH1A1 (0.53) | ALDH1A1LMNATSHRNPC1RAB9A | |
| SCHEMBL967320 | 0.82 | LMNA (0.70) | ALDH1A1LMNATSHRMAPK1NPC1 | |
| Hydrochloric Acid SCHEMBL27708825 | 0.81 | LMNA (0.68) | ALDH1A1LMNATSHRMAPK1NPC1 | |
| SCHEMBL3456186 | 0.81 | LMNA (0.68) | ALDH1A1LMNATSHRMAPK1NPC1 | |
| SCHEMBL1195514 | 0.80 | LMNA (0.78) | ALDH1A1LMNATSHRMAPK1NPC1 | |
| SCHEMBL29100479 | 0.79 | ALDH1A1 (0.66) | ALDH1A1LMNATSHRMAPK1NPC1 | |
| SCHEMBL4075176 | 0.79 | LMNA (0.75) | ALDH1A1LMNATSHRMAPK1NPC1 | |
| SCHEMBL2931129 | 0.79 | ALDH1A1 (0.66) | ALDH1A1LMNATSHRMAPK1NPC1 | |
| SCHEMBL7135592 | 0.79 | NPC1 (0.79) | ALDH1A1MAPK1NPC1TSPORAB9A | |
| SCHEMBL4556798 | 0.78 | LMNA (0.64) | ALDH1A1LMNATSHRMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410726-B1 | S-SUBSTITUTED BETA-THIOACRYLAMIDES AND THEIR USE AS MICROBICIDES | ROHM AND HAAS COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5118681-A | Bactericides | ROHM AND HAAS COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0410726-A1 | S-substituted beta-thioacrylamides and their use as microbicides | ROHM AND HAAS COMPANY (US) | 1991-01-30 | — | — | EP | disclosed |