⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860657 | 0.83 | — | — | |
| SCHEMBL4089787 | 0.83 | TDP1 (0.35) | — | |
| SCHEMBL6191647 | 0.79 | TRPA1 (0.32) | — | |
| SCHEMBL5862013 | 0.77 | — | — | |
| SCHEMBL12201146 | 0.77 | MGAM (0.36) | — | |
| SCHEMBL30992121 | 0.77 | — | — | |
| SCHEMBL10011475 | 0.73 | CYP4F2 (0.43) | — | |
| SCHEMBL5859583 | 0.73 | — | — | |
| SCHEMBL5806950 | 0.72 | GAA (0.32) | — | |
| SCHEMBL10011925 | 0.72 | TSHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239853-B1 | 3,4-DISUBSTITUTED-2-AZETIDINONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-5075437-A | 3,4-DISUBSTITUTED-2-AZETIDINONE DERIVATIVES AND PROCESSES FOR PREPARATION USING TIN ENOLATES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| EP-0239853-A1 | 3,4-Disubstituted-2-azetidinone derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-07 | — | — | EP | disclosed |