Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519239 | 0.91 | BRD4 (0.44) | TP53SMN1; SMN2NPC1RAB9ASCN9A | |
| SCHEMBL9516970 | 0.81 | BCL2L1 (0.48) | HDAC3HDAC1HDAC2NCOR2SMN1; SMN2 | |
| SCHEMBL9519589 | 0.78 | CXCR2 (0.54) | POLBTDP1P4HTMMEN1KMT2A | |
| SCHEMBL9566756 | 0.77 | RAB9A (0.57) | SMN1; SMN2NPC1RAB9AP4HTMALDH1A1 | |
| SCHEMBL9517061 | 0.77 | POLB (0.49) | HDAC3HDAC1HDAC2POLBTDP1 | |
| SCHEMBL2421993 | 0.76 | NR4A2 (0.53) | P4HTMMAPTMEN1KMT2A | |
| SCHEMBL9517881 | 0.76 | GABRA5 (0.53) | HDAC3HDAC1HDAC2NCOR2HDAC11 | |
| SCHEMBL9516029 | 0.76 | NPC1 (0.50) | SMN1; SMN2NPC1RAB9AP4HTMALDH1A1 | |
| SCHEMBL9566764 | 0.75 | TRPV1 (0.60) | SMN1; SMN2NPC1RAB9AALDH1A1NFKB1 | |
| SCHEMBL9517291 | 0.75 | BCL2L1 (0.47) | HDAC3HDAC1HDAC2HDAC11HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |