Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8405112 | 0.84 | HPGDS (0.50) | ALDH1A1HPGDHSD17B10KDM4EGLA | |
| SCHEMBL4513756 | 0.83 | JAK2 (0.54) | SMN1; SMN2CYP2D6CYP2C9CYP2C19PDE4B | |
| SCHEMBL6194819 | 0.76 | USP30 (0.56) | SMN1; SMN2CYP2D6CYP2C9CYP2C19PDE4B | |
| SCHEMBL2324285 | 0.76 | USP30 (0.56) | SMN1; SMN2CYP2D6CYP2C9CYP2C19PDE4B | |
| SCHEMBL13804384 | 0.73 | PARP1 (0.39) | — | |
| SCHEMBL6199606 | 0.73 | POLB (0.31) | POLB | |
| SCHEMBL17001909 | 0.72 | CHRM4 (0.57) | ALDH1A1HPGDHSD17B10KDM4EL3MBTL1 | |
| SCHEMBL12779883 | 0.70 | KDM4E (0.42) | HPGDKDM4ETHRBSMN1; SMN2 | |
| SCHEMBL21138877 | 0.70 | ALDH1A1 (0.57) | ALDH1A1HPGDSMN1; SMN2TSHRHTT | |
| SCHEMBL12258869 | 0.70 | PARP1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296721-B1 | HETEROCYCLIC COMPOUNDS | H. LUNDBECK A/S (DK) | 1993-06-23 | — | — | EP | disclosed |