Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.56 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | DRD5 | P21918 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | BCL9 | O00512 | 2/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21159622 | 0.90 | BRD4 (0.61) | ALDH1A1HPGDLMNAHIF1ABRD4 | |
| SCHEMBL4392358 | 0.89 | PRMT5 (0.56) | ALDH1A1HPGDLMNAHIF1APRMT5 | |
| SCHEMBL29087342 | 0.86 | SMN1; SMN2 (0.59) | ALDH1A1HPGDLMNAHIF1APRMT5 | |
| SCHEMBL28351668 | 0.83 | PRMT5 (0.60) | ALDH1A1LMNAPRMT5WDR77BRD4 | |
| SCHEMBL14035659 | 0.82 | ALDH1A1 (0.61) | ALDH1A1HPGDLMNAHIF1ADRD2 | |
| SCHEMBL6359096 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HPGDLMNAHIF1APRMT5 | |
| SCHEMBL4709679 | 0.81 | PRMT5 (0.64) | ALDH1A1LMNAPRMT5WDR77BRD4 | |
| SCHEMBL248915 | 0.81 | RAB9A (0.50) | ALDH1A1HPGDLMNAHIF1ASMN1; SMN2 | |
| SCHEMBL31233182 | 0.81 | ALDH1A1 (0.59) | ALDH1A1HPGDLMNAHIF1ASMN1; SMN2 | |
| SCHEMBL4033604 | 0.81 | BCL9 (0.81) | BCL9CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3505171-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2019-07-03 | — | — | EP | disclosed |
| US-20190185479-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190185479-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | PDE7B, PDE3A, PDE7A | ALDH1A1 1644/4885HPGD 252/4885LMNA 2370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.