Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 5/20 | 0.46 |
| ▸ | GSK3A | P49840 | 4/20 | 0.46 |
| ▸ | RGS4 | P49798 | 5/20 | 0.42 |
| ▸ | RGS8 | P57771 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521058 | 0.80 | KDM4E (0.47) | KDM4EPKML3MBTL1GSK3BGSK3A | |
| SCHEMBL9868143 | 0.79 | L3MBTL1 (0.53) | KDM4EPKML3MBTL1GSK3BGSK3A | |
| SCHEMBL9868147 | 0.79 | KDM4E (0.49) | KDM4EPKML3MBTL1GSK3BGSK3A | |
| SCHEMBL9519955 | 0.75 | POLB (0.43) | KDM4EGSK3BGSK3AMEN1MAPT | |
| SCHEMBL9521586 | 0.74 | CYP3A4 (0.36) | KDM4EALDH1A1MAPK1 | |
| SCHEMBL9522954 | 0.74 | — | — | |
| SCHEMBL9519978 | 0.72 | NOTUM (0.36) | ALDH1A1NOTUM | |
| SCHEMBL9519526 | 0.67 | GSK3B (0.51) | KDM4EPKML3MBTL1GSK3BGSK3A | |
| SCHEMBL9520206 | 0.67 | GSK3B (0.51) | KDM4EPKML3MBTL1GSK3BGSK3A | |
| SCHEMBL28024350 | 0.67 | TSHR (0.50) | L3MBTL1MEN1KMT2ANOTUMCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008281-A | Insecticides, miticides, nematocides | ROUSSEL UCLAF (FR) | 1991-04-16 | — | — | US | disclosed |
| US-4925862-A | PESTICIDES | ROUSSEL UCLAF (FR) | 1990-05-15 | — | — | US | disclosed |