SCHEMBL9520086

SCHEMBL9520086

O=[N+]([O-])c1[nH]c(Cl)c(-c2ccc(Cl)cc2)c1Br

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.38
MEN1 O00255 3/20 0.38
RAB9A P51151 3/20 0.38
KMT2A Q03164 3/20 0.38
NPC1 O15118 2/20 0.38
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
NPBWR1 P48145 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PKM P14618 2/20 0.36
MCL1 Q07820 2/20 0.36
POLB P06746 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TP53 P04637 1/20 0.36
HCRTR1 O43613 1/20 0.36
PTGS2 P35354 2/20 0.35
GAA P10253 1/20 0.34
PSD A5PKW4 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9224754 0.73 VCAM1 (0.37) MAPTMEN1RAB9AKMT2ANPC1
SCHEMBL9015085 0.71 MAPT (0.42) MAPTMEN1RAB9AKMT2ANPC1
SCHEMBL28072347 0.70 PTGS2 (0.53) MAPTKMT2AALDH1A1HPGDPKM
SCHEMBL9520176 0.69 MAPT (0.43) MAPTMEN1RAB9AKMT2ANPC1
SCHEMBL9840656 0.67 PSD (0.42) MAPTMEN1RAB9AKMT2ANPC1
SCHEMBL9518736 0.67 MAPT (0.35) MAPTMEN1RAB9AKMT2ANPC1
SCHEMBL9518638 0.66 ALDH1A1 (0.43) MAPTMEN1RAB9AKMT2ANPC1
SCHEMBL9015042 0.65 HSD17B10 (0.40) MAPTMEN1KMT2AHTTPKM
SCHEMBL9337605 0.64 MAPT (0.38) MAPTMEN1RAB9AKMT2ANPC1
SCHEMBL2333608 0.64 CYP1A2 (0.60) MAPTMEN1RAB9AKMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0312723-B1 Method of and bait compositions for controlling mollusks AMERICAN CYANAMID CO (US) 1993-12-22 EP disclosed
US-5010098-A Arylpyrrole insecticidal acaricidal and nematicidal agents and methods for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1991-04-23 US disclosed
US-4929634-A ARYLPYRROLE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 1990-05-29 US disclosed
EP-0347488-A1 Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1989-12-27 EP disclosed
EP-0312723-A2 Method of and bait compositions for controlling mollusks AMERICAN CYANAMID COMPANY (US) 1989-04-26 EP disclosed