Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.40 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.40 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.40 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.40 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GALK1 | P51570 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13560566 | 0.90 | MAPK1 (0.41) | MAPK1SYNJ2KDM4EABL1ALPL | |
| SCHEMBL3636324 | 0.80 | SYNJ2 (0.59) | SYNJ2KDM4EABL1ALPLPOLB | |
| SCHEMBL1239229 | 0.80 | SYNJ2 (0.43) | SYNJ2KDM4EABL1ALPLPOLB | |
| SCHEMBL8218275 | 0.78 | SLC6A2 (0.43) | SYNJ2KDM4EABL1ALPLPOLB | |
| SCHEMBL20225121 | 0.76 | MAPK1 (0.48) | MAPK1LGALS9LGALS1LGALS3LGALS8 | |
| SCHEMBL27798327 | 0.74 | TYR (0.45) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8 | |
| SCHEMBL1239221 | 0.74 | SYNJ2 (0.53) | SYNJ2KDM4EABL1ALPLPOLB | |
| SCHEMBL5336720 | 0.74 | SYNJ2 (0.53) | SYNJ2KDM4EABL1ALPLPOLB | |
| SCHEMBL9838031 | 0.73 | PTPN1 (0.38) | MAPK1LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL7164875 | 0.73 | PTPN1 (0.38) | MAPK1LGALS9LGALS1LGALS3LGALS7; LGALS7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302253-B1 | 3-DEMETHYL-4-FLUORO-MEVALONIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS BASED ON THOSE COMPOUNDS, THEIR USE AND INTERMEDIATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-04-07 | — | — | EP | disclosed |
| US-4898868-A | ANTICHOLESTEROL AGENTS; LACTONE OR FREE ACID FORM | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-06 | — | — | US | disclosed |