Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521004 | 0.87 | NOTUM (0.31) | — | |
| SCHEMBL9522911 | 0.86 | NPC1 (0.31) | — | |
| SCHEMBL9521073 | 0.85 | NOTUM (0.35) | TSHRHSD17B10LCKFYN | |
| SCHEMBL9519992 | 0.72 | PTPN11 (0.31) | — | |
| SCHEMBL9494830 | 0.71 | NOTUM (0.38) | — | |
| SCHEMBL9706620 | 0.71 | BRD9 (0.34) | TSHR | |
| SCHEMBL9706711 | 0.65 | HPGD (0.33) | — | |
| SCHEMBL9706623 | 0.64 | TTR (0.32) | LCKFYN | |
| SCHEMBL21352106 | 0.63 | HSD17B10 (0.50) | TSHRHSD17B10LCKFYN | |
| SCHEMBL25407247 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323487-B1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | claimed |