Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9522648 | 0.99 | RAB9A (0.47) | RAB9AMAPK1SMN1; SMN2SIGMAR1KDM2B | |
| SCHEMBL8303218 | 0.82 | MEN1 (0.39) | MAPK1L3MBTL1TSHR | |
| SCHEMBL8873628 | 0.82 | L3MBTL1 (0.47) | MAPK1L3MBTL1HTR7TSHR | |
| SCHEMBL16256954 | 0.81 | RAB9A (0.59) | RAB9AMAPK1SIGMAR1KDM2BL3MBTL1 | |
| SCHEMBL8304050 | 0.79 | HRH2 (0.47) | MAPK1SMN1; SMN2L3MBTL1HTR7DRD2 | |
| Hydrochloric Acid SCHEMBL8306472 | 0.78 | HRH2 (0.46) | MAPK1SMN1; SMN2L3MBTL1HTR7DRD2 | |
| SCHEMBL8303793 | 0.76 | GAA (0.49) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL8303345 | 0.74 | CYP2D6 (0.43) | SMN1; SMN2TSHR | |
| SCHEMBL11932602 | 0.73 | RAB9A (0.55) | RAB9AMAPK1L3MBTL1HTR7THRB | |
| SCHEMBL10673408 | 0.71 | GLB1 (0.52) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301245-B1 | 3-SULFONYL-3,7-DIAZABICYCLO-(3,3,1)NONANE COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND MEDICAMENTS CONTAINING THESE COMPOUNDS | Kali-Chemie Pharma GmbH (DE) | 1993-09-08 | — | — | EP | disclosed |
| US-4983611-A | TREATING A STOMACH MOTILITY DISTURBANCE | KALI-CHEMIE PHARMA GMBH (DE) | 1991-01-08 | — | — | US | disclosed |
| US-4906640-A | 3-sulfonyl-3,7-diazabicyclo[3,3,1]nonane compounds and medicaments containing said compounds | KALI-CHEMIE PHARMA GMBH (DE) | 1990-03-06 | — | — | US | disclosed |