Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873628 | 0.88 | L3MBTL1 (0.47) | MEN1KMT2AMMP2TSHRMAPK1 | |
| SCHEMBL8304050 | 0.84 | HRH2 (0.47) | MEN1KMT2ATSHRMAPK1RECQL | |
| Hydrochloric Acid SCHEMBL8306472 | 0.83 | HRH2 (0.46) | MEN1KMT2ATSHRMAPK1RECQL | |
| SCHEMBL9520302 | 0.82 | RAB9A (0.45) | TSHRMAPK1L3MBTL1 | |
| SCHEMBL8303793 | 0.82 | GAA (0.49) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9522648 | 0.81 | RAB9A (0.47) | TSHRMAPK1L3MBTL1 | |
| SCHEMBL8303345 | 0.79 | CYP2D6 (0.43) | TSHRCYP19A1ALDH1A1LMNAHTT | |
| SCHEMBL10673408 | 0.74 | GLB1 (0.52) | — | |
| SCHEMBL8306366 | 0.74 | KMT2A (0.49) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL9235427 | 0.73 | PKM (0.45) | L3MBTL1ALDH1A1HTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665228-B1 | Pharmaceutical compositions containing 3-phenylsulfonyl-3,7-diazabicyclo 3,3,1 nonanes | SOLVAY PHARM GMBH (DE) | 1999-07-14 | — | — | EP | disclosed |
| US-5576327-A | Treatment of heart rhythym disorders by administration of 3-phenylsulfonyl-3, 7-diazabicyclo[3.3.1]nonane compounds | KALI-CHEMIE PHARMA GMBH (DE) | 1996-11-19 | — | — | US | disclosed |
| EP-0665228-A1 | Pharmaceutical compositions containing 3-phenylsulfonyl-3,7-diazabicyclo 3,3,1 nonanes | Kali-Chemie Pharma GmbH (DE) | 1995-08-02 | — | — | EP | disclosed |