Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28257145 | 0.85 | CTSK (0.47) | CHUKCTSKKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL3917850 | 0.73 | CTSK (0.60) | CHUKCTSKCTSLCTSSCTSB | |
| SCHEMBL17008748 | 0.71 | PDE4A (0.37) | CHUKCTSKKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9521151 | 0.69 | ALOX5AP (0.37) | CTSKKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL137039 | 0.67 | USP8 (0.35) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL23782292 | 0.67 | CTSK (0.40) | CHUKCTSKKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL11650165 | 0.67 | ALDH1A1 (0.50) | CHUKCTSKKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL3925553 | 0.66 | KMT2A (0.62) | CTSKCTSLCTSSCTSBNSD2 | |
| SCHEMBL15273450 | 0.66 | CHUK (0.45) | CHUKCTSKKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9519918 | 0.66 | LMNA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308895-B1 | DICYANOPYRAZINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND FUNGICIDE | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-5093335-A | Agricultural and horticultural | HODOGAYA CHEMICAL COMPANY, LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0308895-A1 | Dicyanopyrazine compounds, process for their preparation and fungicide | HODOGAYA CHEMICAL CO., LTD. (JP) | 1989-03-29 | — | — | EP | disclosed |