Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | RPS27 | P42677 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520382 | 0.78 | LMNA (0.39) | LMNAPOLBHTT | |
| SCHEMBL9522570 | 0.77 | KDM4E (0.38) | LMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL29437694 | 0.71 | USP8 (0.35) | HTTMAPT | |
| SCHEMBL137039 | 0.71 | USP8 (0.35) | HTTMAPT | |
| SCHEMBL9356027 | 0.67 | USP8 (0.41) | — | |
| SCHEMBL7859690 | 0.66 | KHK (0.45) | LMNAHTTCCNA2CDK2TTK | |
| SCHEMBL507982 | 0.66 | USP8 (0.44) | HTTMAPT | |
| SCHEMBL9520355 | 0.66 | CHUK (0.45) | — | |
| SCHEMBL13514616 | 0.65 | MAPK8 (0.53) | HTTCCNA2CDK2TTKRPS27 | |
| SCHEMBL1732586 | 0.61 | KDM4E (0.45) | LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308895-B1 | DICYANOPYRAZINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND FUNGICIDE | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-5093335-A | Agricultural and horticultural | HODOGAYA CHEMICAL COMPANY, LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0308895-A1 | Dicyanopyrazine compounds, process for their preparation and fungicide | HODOGAYA CHEMICAL CO., LTD. (JP) | 1989-03-29 | — | — | EP | disclosed |