Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752167 | 0.83 | RAB9A (0.46) | RAB9ANPC1MAPTALDH1A1HPGD | |
| Mivotilate SCHEMBL8752155 | 0.82 | MAPT (0.43) | RAB9ANPC1MAPTALDH1A1HPGD | |
| SCHEMBL11225467 | 0.80 | MAPT (0.62) | RAB9ANPC1MAPTALDH1A1HPGD | |
| SCHEMBL1691061 | 0.75 | MAPT (0.68) | RAB9ANPC1MAPTALDH1A1HPGD | |
| SCHEMBL9523229 | 0.75 | MAPT (0.43) | RAB9ANPC1MAPTALDH1A1HPGD | |
| SCHEMBL10816647 | 0.71 | RAB9A (0.71) | RAB9ANPC1MAPTALDH1A1HPGD | |
| SCHEMBL11225869 | 0.71 | MAPT (0.58) | RAB9ANPC1MAPTALDH1A1HPGD | |
| SCHEMBL8752175 | 0.70 | L3MBTL1 (0.48) | RAB9ANPC1MAPTALDH1A1GAA | |
| SCHEMBL48394 | 0.70 | MAPT (0.66) | RAB9ANPC1MAPTALDH1A1HPGD | |
| SCHEMBL19994395 | 0.70 | MAPT (0.66) | RAB9ANPC1MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366614-B1 | PHARMACEUTICALLY ACTIVE DITHIOKETENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1993-09-01 | — | — | EP | disclosed |
| US-5103013-A | For treating liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-04-07 | — | — | US | disclosed |