Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523229 | 0.93 | MAPT (0.43) | MAPTRAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL8752149 | 0.87 | ADRA1A (0.55) | MAPTRAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL8752175 | 0.86 | L3MBTL1 (0.48) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8752167 | 0.84 | RAB9A (0.46) | MAPTRAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL9520912 | 0.82 | MAPT (0.49) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9520587 | 0.82 | RAB9A (0.49) | MAPTRAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL8752169 | 0.81 | PKM (0.48) | RAB9ANPC1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL9521789 | 0.80 | CTSK (0.41) | RAB9ANPC1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL13694514 | 0.75 | MAPT (0.55) | MAPTRAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL9521170 | 0.74 | SMN1; SMN2 (0.50) | MAPTRAB9ANPC1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4484426-A1 | PYRIMIDO AROMATIC RING COMPOUND AND USE THEREOF IN DRUG | Sunshine Lake Pharma Co., Ltd. (CN) | 2025-01-01 | — | — | EP | claimed |
| US-12128044-B2 | Fused tricyclic compounds and uses thereof in medicine | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2024-10-29 | — | — | US | claimed |
| EP-3694856-B1 | FUSED TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO LTD (CN) | 2023-10-25 | — | — | EP | claimed |
| US-11773098-B2 | Solid forms of a toll-like receptor modulator | GILEAD SCIENCES, INC. (US) | 2023-10-03 | — | — | US | claimed |
| WO-2023160527-A1 | PYRIMIDO AROMATIC RING COMPOUND AND USE THEREOF IN DRUG | 广东东阳光药业股份有限公司 | 2023-08-31 | — | — | WO | claimed |
| WO-2022156758-A1 | NOVEL AMIDE PYRROLE COMPOUND AND USE THEREOF IN DRUGS | 广东东阳光药业有限公司 | 2022-07-28 | — | — | WO | claimed |
| WO-2022143610-A1 | NOVEL AMIDE PYRROLE COMPOUNDS AND USE THEREOF IN MEDICAMENTS | 广东东阳光药业有限公司 | 2022-07-07 | — | — | WO | claimed |
| US-20220194951-A1 | DIHYDROPYRIMIDINE COMPOUND AND APPLICATION THEREOF AS DRUG | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-06-23 | — | — | US | claimed |
| US-11261190-B2 | Dihydropyrimidine compounds and uses thereof in medicine | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-03-01 | — | — | US | claimed |
| EP-0782854-A2 | Use of isopropyl-2-(1,3-dithietan-2-ylidene)-2-(N-(4-methylthiazol-2-yl)carbamoyl)acetate as a cancer chemopreventive agent | Yuhan Corporation (KR) | 1997-07-09 | — | — | EP | claimed |
| EP-0766560-A1 | USE OF THIOKETENE DERIVATIVES FOR PREVENTING OR TREATING HEPATITIS B | YUHAN CORPORATION, LTD. (KR) | 1997-04-09 | — | — | EP | claimed |
| WO-1996033711-A2 | USE OF THIOKETENE DERIVATIVES FOR PREVENTING OR TREATING HEPATITIS B | YUHAN CORPORATION (KR) | 1996-10-31 | — | — | WO | claimed |
| JP-9249564-A | — | — | None | — | — | JP | disclosed |
| CN-122036801-A | Crystalline forms of tenofovir alafenamide | 吉利德科学公司 | 2026-05-15 | — | — | CN | disclosed |
| EP-3870566-B1 | PD-1/PD-L1 INHIBITORS | GILEAD SCIENCES INC (US) | 2026-05-06 | — | — | EP | disclosed |
| EP-4234030-B1 | PD-1/PD-L1 INHIBITORS | GILEAD SCIENCES INC (US) | 2026-04-08 | — | — | EP | disclosed |
| EP-0766560-A1 | USE OF THIOKETENE DERIVATIVES FOR PREVENTING OR TREATING HEPATITIS B | YUHAN CORPORATION, LTD. (KR) | 1997-04-09 | — | — | EP | disclosed |
| WO-1996033711-A2 | USE OF THIOKETENE DERIVATIVES FOR PREVENTING OR TREATING HEPATITIS B | YUHAN CORPORATION (KR) | 1996-10-31 | — | — | WO | disclosed |
| EP-0366614-B1 | PHARMACEUTICALLY ACTIVE DITHIOKETENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1993-09-01 | — | — | EP | disclosed |
| US-5103013-A | For treating liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12128044-B2 | Fused tricyclic compounds and uses thereof in medicine | SLC10A1, CYP11B1, CYP11B2 | MAPT 123/4885RAB9A 3503/4885NPC1 102/4885 |
| US-20220194951-A1 | DIHYDROPYRIMIDINE COMPOUND AND APPLICATION THEREOF AS DRUG | DHODH, DPYD, SLC10A1 | MAPT 63/4885RAB9A 3842/4885NPC1 660/4885 |
| US-11773098-B2 | Solid forms of a toll-like receptor modulator | TLR4, TLR3, TLR6 | MAPT 3799/4885RAB9A 3927/4885NPC1 2401/4885 |
| US-11261190-B2 | Dihydropyrimidine compounds and uses thereof in medicine | DPYD, TPMT, SLC10A1 | MAPT 181/4885RAB9A 3634/4885NPC1 414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.