Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mivotilate SCHEMBL8752155 | 0.93 | MAPT (0.43) | MAPTRAB9AEPHX2NPC1SMN1; SMN2 | |
| SCHEMBL8752149 | 0.87 | ADRA1A (0.55) | MAPTRAB9AEPHX2NPC1SMN1; SMN2 | |
| SCHEMBL8752175 | 0.79 | L3MBTL1 (0.48) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8752167 | 0.77 | RAB9A (0.46) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9520912 | 0.76 | MAPT (0.49) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13694514 | 0.75 | MAPT (0.55) | MAPTRAB9AEPHX2NPC1SMN1; SMN2 | |
| SCHEMBL9520587 | 0.75 | RAB9A (0.49) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8752169 | 0.73 | PKM (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM | |
| Isoprothiolane SCHEMBL71267 | 0.72 | ADRA1A (0.60) | RAB9ANPC1SMN1; SMN2TSHR | |
| Isoprothiolane SCHEMBL8408577 | 0.72 | ADRA1A (0.60) | RAB9ANPC1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366614-B1 | PHARMACEUTICALLY ACTIVE DITHIOKETENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1993-09-01 | — | — | EP | disclosed |
| US-5103013-A | For treating liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-04-07 | — | — | US | disclosed |