Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | HTR1D | P28221 | 5/20 | 0.40 |
| ▸ | HTR1B | P28222 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521081 | 0.82 | MAPT (0.41) | MAPTTP53MAPK1MEN1ALDH1A1 | |
| SCHEMBL9523548 | 0.81 | S1PR1 (0.45) | CYP3A4CYP2D6S1PR1 | |
| SCHEMBL9521541 | 0.80 | AOC3 (0.43) | MAPTALDH1A1CYP3A4CYP2D6HPGD | |
| SCHEMBL9521718 | 0.76 | CYP3A4 (0.55) | MAPTHTR1DHTR1BHTR2ATP53 | |
| SCHEMBL9520566 | 0.75 | NR1I2 (0.44) | MAPTMAPK1CYP3A4CYP2D6HPGD | |
| SCHEMBL9520549 | 0.73 | CYP3A4 (0.51) | MAPTHTR1DHTR1BHTR2ATP53 | |
| SCHEMBL9521817 | 0.73 | CYP3A4 (0.51) | MAPTHTR1DHTR1BHTR2ATP53 | |
| SCHEMBL9522218 | 0.72 | MAPT (0.39) | MAPTTP53KDM4EMEN1ALDH1A1 | |
| SCHEMBL12112418 | 0.72 | PLK1 (0.52) | MAPTTP53MAPK1HPGDHTT | |
| SCHEMBL12266918 | 0.70 | PLK1 (0.56) | MAPTHTR1DHTR1BHTR2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523803-A1 | 1,2,4-Oxadiazolyl-phenoxy-alkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1993-01-20 | — | — | EP | disclosed |