Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | POLB | P06746 | 8/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520640 | 0.82 | MAPT (0.40) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL9523548 | 0.81 | S1PR1 (0.45) | S1PR1 | |
| SCHEMBL9521541 | 0.80 | AOC3 (0.43) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9521623 | 0.79 | NPC1 (0.44) | MAPTPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9521718 | 0.76 | CYP3A4 (0.55) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL8135973 | 0.76 | NR1I2 (0.61) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9520566 | 0.75 | NR1I2 (0.44) | MAPTMAPK1HPGDLMNA | |
| SCHEMBL9521817 | 0.73 | CYP3A4 (0.51) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL9520549 | 0.73 | CYP3A4 (0.51) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL9522218 | 0.72 | MAPT (0.39) | MAPTPOLBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523803-A1 | 1,2,4-Oxadiazolyl-phenoxy-alkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1993-01-20 | — | — | EP | disclosed |