Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8137092 | 0.80 | SCN8A (0.41) | MAOBCA12CA9MAOAHSP90B1 | |
| SCHEMBL10764567 | 0.77 | PLAU (0.34) | HPGDL3MBTL1MAPTMAPK1PLAU | |
| SCHEMBL9523339 | 0.74 | SCN8A (0.39) | MAOBMAOAMAPTSCN8A | |
| SCHEMBL8876567 | 0.74 | SCN8A (0.39) | MAOBMAOAMAPTSCN8A | |
| SCHEMBL9521685 | 0.72 | HRH3 (0.50) | MAOBCA12CA9MAOAMAPT | |
| SCHEMBL13623362 | 0.71 | ALDH1A1 (0.35) | MAOBCA12CA9MAOAHSP90B1 | |
| SCHEMBL8875626 | 0.67 | NR1I2 (0.45) | HPGDL3MBTL1MAPTMAPK1 | |
| SCHEMBL9376589 | 0.67 | MAOB (0.57) | MAOBMAPK1MRGPRX4 | |
| SCHEMBL9786326 | 0.66 | ALDH3A1 (0.50) | MAOBCA12CA9MAOA | |
| SCHEMBL920034 | 0.63 | MAOB (0.44) | MAOBCA12CA9MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523803-A1 | 1,2,4-Oxadiazolyl-phenoxy-alkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5175177-A | 1,2,4-OXADIAZOLYL-PHENOXYALKYLISOXAZOLES AND THEIR USE AS ANTIVIRAL AGENTS | STERLING DRUG INC. (US) | 1992-12-29 | — | — | US | disclosed |